The homeostatic regulatory system of the body. The Endocannabinoid System, or ECS, found in all mammals, affects every physiological process, including appetite, regulation of mood and perception of pain. It is considered one of the most important physiologic systems involved in establishing and maintaining human health, playing a key role in regulating pain, mood, memory, appetite, immune function, inflammation, blood pressure, bone growth, the protection of neural tissues and dozens of other physiological processes.